Disease Background – Why Dry Eyes Matter 👁️ Dry Eye Syndrome (DES) is a multifactorial disease that affects the tear film and ocular surface.  It can be caused by aging, screen overuse, medications, or environmental stress. ⚠️ Disruption of the corneal epithelium leads to:  – 🔥 Inflammation  – 😣 Irritation and burning sensation  – 🌫️ Blurred vision  – 🩹 Delayed healing and increased infection risk 💧 Protecting and restoring the corneal barrier is essential for long-term eye health. 🔬 Clinical Evidence – Proven by Science 📊 A randomized, double-blind, controlled clinical study investigated the efficacy of Dexpanthenol in managing dry eyes, showing:  ✅ Improved corneal epithelial permeability – a critical marker in ocular surface recovery  ✅ Significant symptom relief within 2 weeks, with marked improvement by week 6  ✅ Better healing outcomes compared to placebo or standard artificial tears  ✅ Enhanced tear film stability and moisture retention 👩⚕️ Patients using Dexpanthenol-containing drops (such as GELB5 Eye) experienced:  ✨ Fewer dry spots  ✨ Reduced ocular surface damage  ✨ Higher comfort and satisfaction 💧 Advanced Formulation Formulated with Carbomer for prolonged contact time and Liquidshield™ Technology for sustained hydration.  🚫 No preservatives  🚫 No irritation  ✅ Suitable for long-term or sensitive use 🌟 Choose GELB5 Eye – where clinical science meets daily comfort and healing.

To Physiatrists - Post 2 of 4: Neurogenic Bladder/Bowel Solutions Neurogenic incontinence is one of your most challenging complications—unpredictable, difficult to manage, and devastating for patient morale. Here's what the Curaco Carebidet does for neurogenic dysfunction: **The Complete System:** ✓ **Continuous Monitoring**: Sensors detect both urinary and fecal incontinence instantly—no matter how unpredictable ✓ **Immediate Response**: Automated cleaning begins within seconds of detection ✓ **Handles All Consistency**: Manages liquid, formed, or mixed stool from neurogenic bowel ✓ **Gentle Cleansing**: Adjustable water pressure respects sensitive skin and surgical sites ✓ **Complete Drying**: Warm air prevents moisture-related complications **Clinical outcomes for rehab patients:** • 63% reduction in hands-on hygiene care time • Significantly lower pressure ulcer development • Reduced UTI rates from immediate cleaning • Better therapy compliance (no embarrassment) • Improved patient motivation and mental health **Perfect for patients with:** • Spinal cord injury (complete or incomplete) • Stroke with bowel/bladder dysfunction • Multiple sclerosis • Parkinson's disease • Traumatic brain injury FDA 510(k)-exempt | CMS-recognized | Billable E2001/A9286 👉 Follow for rehabilitation innovations! 📅 See it in action: https://lnkd.in/gnjsUYzb Next: Real patient scenarios →

Abstract: The Terrain-Level Determinants of Ischemic Stroke — An ALH–eGFR Framework for Precision Prevention While ischemic stroke is classically categorized by mechanism—embolism, thrombosis, dissection, or small-vessel disease—these visible outcomes emerge from deeper, measurable changes in the body’s terrain. In this integrated framework, stroke risk is redefined not as an isolated vascular event but as the endpoint of cumulative terrain erosion. Declining eGFR (estimated glomerular filtration rate), endothelial microinjury, oxidative stress, dehydration, and allostatic overload together alter plasma viscosity, shear dynamics, and mitochondrial resilience—conditions that silently prepare the vasculature for failure. Likewise, caregiving stress, malnutrition, and iatrogenic medication patterns accelerate inflammatory cascades and vascular fragility. The ALH Caregiver Index, paired with eGFR trajectories, identifies early inflection points where preventive interventions—hydration, oxygenation, rhythm regulation, cooling therapy, and caregiver education—can preserve neuronal integrity and reduce stroke incidence. This terrain-based model reframes prevention around upstream metrics of biological and behavioral health, bridging patient care, public health, and precision medicine.

In addition to treating inflammation in patients with polymyalgia rheumatica (PMR), clinicians should include mobility and independence as explicit targets of care due to the associated functional decline in this population. A proposed function modification PMR model includes the following steps: 1. Assess and track functional performance in the clinic using feasible and prognostic measures (e.g., gait speed, 5-times sit-to-stand, and Short Physical Performance Battery). 2. Provide early education on the importance of staying active, with referral to physiotherapy as needed, to prescribe individualized progressive resistance training for girdle muscles, balance/coordination exercises, and aerobic conditioning—dosing tailored to disease status. Physiotherapists emphasize the value of physical therapy in supporting people with PMR. 3. Assess fracture risk, including pharmacologic interventions and fall-prevention strategies. These steps should run parallel to pharmacologic management, including glucocorticoids and glucocorticoid-sparing therapies, aiming for remission or low disease activity while optimizing daily function. *From: O’Brien AV, Sattui SE. From symptom amelioration to function modification: is it time to expand the treatment focus in polymyalgia rheumatica? Rheumatology (Oxford), 2025.  🔗https://lnkd.in/dBiuZr5i

Psoriasis is one of the best-treated inflammatory diseases in medicine today with treatments helping nearly 9 out of 10 patients achieve completely clear skin. 🙌 What was once a challenging condition is now setting the standard for how we approach other complex diseases like cancers, autoimmune, and neurological disorders. Here at OMRC, we’re proud to contribute to this progress through ongoing clinical research and innovation. 💜 - La psoriasis es hoy en día una de las enfermedades inflamatorias con mejor tratamiento en la medicina, con terapias que ayudan a casi 9 de cada 10 pacientes a lograr una piel completamente libre de lesiones. 🙌 Lo que antes era una condición difícil de tratar, ahora marca el estándar de cómo abordamos otras enfermedades complejas como el cáncer, los trastornos autoinmunes y neurológicos. En OMRC, nos enorgullece contribuir a este progreso a través de la investigación clínica y la innovación continua. 💜 #WorldPsoriasisDay #OMRC #PsoriasisAwareness #ClinicalResearch #SkinHealth

PLEURAL EFFUSION :- • Pleural effusion is the abnormal accumulation of fluid in the pleural space, impairing gas exchange and lung expansion. It is classified as either:🔹 Transudative (Watery Fluid) :-• Caused by systemic factors (↑ hydrostatic or ↓ oncotic pressure)  • Common causes:     - Heart failure     - End-stage renal disease     - Liver cirrhosis with ascites  🔹 Exudative (Protein-Rich/Thicker Fluid) :-• Caused by local inflammation or malignancy  • Common causes:     - Malignancy     - Pulmonary embolism     - Tuberculosis  🔍 Signs & Symptoms :-• May be asymptomatic  • Dyspnea (SOB)  • Pleuritic chest pain  • ↓ Breath sounds or absent on auscultation  🧪 Diagnostic Tests :-• Chest X-ray, ultrasound  • Thoracentesis for fluid analysis  • Physical exam (↓ breath sounds, dull percussion)  💉 Treatment :-  • Thoracentesis  • Treat underlying cause (e.g., antibiotics)  💡 Nursing Interventions :-  • Monitor respiratory status, vital signs  • Position in High Fowler’s  • Administer O2 as needed  • Pain control  • Encourage deep breathing, incentive spirometry  📚 Client Education :-• Report worsening symptoms: SOB, cyanosis, bloody sputum⚠️ Complications :-• Pneumothorax  • Empyema  • Lung fibrosis  

الحمدلله الذي بنعمته تتم الصالحات It gives me pleasure to share our latest Publication under Moorfields Eye Hospital UAE on Ramadan fasting and Diabetic retinopathy. This is an international Multi-center, retrospective cohort review of 12,000 patients in Association with Diabetes and Ramadan (DaR) association and The International Diabetes Federation (IDF). Endocrinologists in UAE, Gulf and Muslim world use a stratified scoring system to decide on the safety of Ramadan fasting for Diabetic patients. DR is not one of these criteria. The Aim of this study is to assess the association of DR and its need to be added to the scoring system used by endocrinologists. We found: patients with DR were independently linked to lower fasting rates and higher risks of hypoglycemia, hyperglycemia, and medical interventions during Ramadan in comparasion to control group. These findings underscore the importance of incorporating DR assessment into fasting risk stratification tools to improve patient safety. Hopefully, the outcome of this paper will lead to a change in risk assessment guidelines for DM and Ramadan fasting patients.

A simple yet surprising clinical observation on Overactive Bladder Overactive bladder is caused by an abnormal entry of calcium ions into the bladder smooth muscle cells through pathways other than physiological ones. The increase in intracellular calcium triggers microcontractions that increase bladder tone, facilitate the opening of the first sphincter, and can lead to urinary leakage. Sensory afferents to the spinal cord and brain amplify signals from the bladder, generating pain, urgency, and incontinence, the latter resulting from incoordination. Under normal conditions, however, only a painless sense of fullness is perceived. beta blocker reduces adrenergic hyperactivity secondary to stress, decreases the release of norepinephrine and ATP, and raises the contraction threshold of the detrusor muscle. I have successfully used atenolol 25 mg/day on myself, as a sufferer of overactive bladder, and on five other patients, achieving complete remission of symptoms in all cases.

🩵 Disease Background – Why Dry Eyes Matter 👁️ Dry Eye Syndrome (DES) is a multifactorial disease that affects the tear film and ocular surface. It can be caused by aging, screen overuse, medications, or environmental stress. ⚠️ Disruption of the corneal epithelium leads to: – 🔥 Inflammation – 😣 Irritation and burning sensation – 🌫️ Blurred vision – 🩹 Delayed healing and increased infection risk 💧 Protecting and restoring the corneal barrier is essential for long-term eye health. 🔬 Clinical Evidence – Proven by Science 📊 A randomized, double-blind, controlled clinical study investigated the efficacy of Dexpanthenol in managing dry eyes, showing: ✅ Improved corneal epithelial permeability – a critical marker in ocular surface recovery ✅ Significant symptom relief within 2 weeks, with marked improvement by week 6 ✅ Better healing outcomes compared to placebo or standard artificial tears ✅ Enhanced tear film stability and moisture retention 👩⚕️ Patients using Dexpanthenol-containing drops (such as GELB5 Eye) experienced: ✨ Fewer dry spots ✨ Reduced ocular surface damage ✨ Higher comfort and satisfaction 💧 Advanced Formulation Formulated with Carbomer for prolonged contact time and Liquidshield™ Technology for sustained hydration. 🚫 No preservatives 🚫 No irritation ✅ Suitable for long-term or sensitive use 🌟 Choose GELB5 Eye – where clinical science meets daily comfort and healing.

Blood Thinners May No Longer Be Needed for Many with Irregular Heartbeats A new study has revealed that many patients with atrial fibrillation (AFib), a common condition causing irregular heartbeats, may no longer require daily blood thinners to prevent strokes. Traditionally, medications such as warfarin or newer direct oral anticoagulants (DOACs) were prescribed to prevent clot formation, which can lead to heart attacks or strokes. Researchers found that with advanced heart monitoring and improved rhythm control, patients with mild or well-managed AFib may safely reduce or even discontinue long-term use of blood thinners under medical supervision. This represents a major shift toward personalized treatment, where therapy is based on an individual’s heart rhythm patterns rather than a one-size-fits-all approach. This change could lower the risks associated with blood thinners, such as internal bleeding, while simplifying patient care and reducing medication costs. However, experts emphasize that not all patients can stop these drugs; those with high-risk conditions like hypertension, diabetes, or prior stroke still need preventive treatment. The study highlights how digital health monitoring and precision medicine are transforming cardiology, offering safer and more adaptive care options for millions living with AFib worldwide. For full details and to collect engagement points, follow @Miraba.Health or Toronto Health Hub on Instagram & X.